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#autophagy

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eLife<p>This fundamental study looks at the role of Ezrin, a membrane-actin linker that assembles signalling complexes, unveiling a critical endosome–lysosome network essential for <a href="https://fediscience.org/tags/autophagy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>autophagy</span></a> and cellular <a href="https://fediscience.org/tags/homeostasis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>homeostasis</span></a>.<br><a href="https://elifesciences.org/articles/98523?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">elifesciences.org/articles/985</span><span class="invisible">23?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic</span></a></p>
PLOS Biology<p>Caspases have well known roles in <a href="https://fediscience.org/tags/apoptosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>apoptosis</span></a>, but roles in other cellular processes are emerging... This study shows that <a href="https://fediscience.org/tags/caspase" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>caspase</span></a> -3 &amp; -7 promote cytoprotective <a href="https://fediscience.org/tags/autophagy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>autophagy</span></a> in response to non-lethal stress by modulating PARP1 activity in <a href="https://fediscience.org/tags/BreastCancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BreastCancer</span></a> cells <a href="https://fediscience.org/tags/plosbiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>plosbiology</span></a> <a href="https://plos.io/41xfLVm" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="">plos.io/41xfLVm</span><span class="invisible"></span></a></p>
CellBioNews<p><a href="https://scientificnetwork.de/tags/Cellular" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Cellular</span></a> clean-up: Solving the mystery of how cells initiate their recycling process.</p><p><a href="https://scientificnetwork.de/tags/PI3_kinase" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PI3_kinase</span></a> <a href="https://scientificnetwork.de/tags/VPS15" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>VPS15</span></a> <a href="https://scientificnetwork.de/tags/autophagy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>autophagy</span></a></p><p> <a href="https://phys.org/news/2025-02-cellular-mystery-cells-recycling.html" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">phys.org/news/2025-02-cellular</span><span class="invisible">-mystery-cells-recycling.html</span></a></p>
Charrvein<p>Roles of the autophagy gene ATG7 in health and disease</p><p>Margrét Helga Ögmundsdóttir talk at <a href="https://mastodon.online/tags/UniversityIceland" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>UniversityIceland</span></a> </p><p>The essential mammalian gene, ATG7, has been widely studied in connection with autophagy.&nbsp;<br><a href="https://mastodon.online/tags/cellbiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cellbiology</span></a> <a href="https://mastodon.online/tags/autophagy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>autophagy</span></a> <a href="https://mastodon.online/tags/genetics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>genetics</span></a> <a href="https://mastodon.online/tags/evolution" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>evolution</span></a> <a href="https://mastodon.online/tags/Iceland" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Iceland</span></a> <a href="https://mastodon.online/tags/atg7" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>atg7</span></a> <a href="https://mastodon.online/tags/atg8" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>atg8</span></a></p><p><a href="https://hi.is/vidburdir/malstofa_lifvisindaseturs_roles_of_the_autophagy_gene_atg7_in_health_and_disease" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">hi.is/vidburdir/malstofa_lifvi</span><span class="invisible">sindaseturs_roles_of_the_autophagy_gene_atg7_in_health_and_disease</span></a></p>
PLOS Biology<p>What is the mechanistic link between the NLRP3 <a href="https://fediscience.org/tags/inflammasome" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammasome</span></a>, <a href="https://fediscience.org/tags/autophagy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>autophagy</span></a> &amp; inflammatory <a href="https://fediscience.org/tags/bowel" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>bowel</span></a> disease (IBD)? This study shows that VANGL2 reduces <a href="https://fediscience.org/tags/IBD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>IBD</span></a> progression by recruiting the ubiquitin ligase MARCH8 to regulate NLRP3 activation via OPTN-mediated autophagy plosbiology <a href="https://plos.io/42FTqFO" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="">plos.io/42FTqFO</span><span class="invisible"></span></a></p>
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